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How Long Does Ativan (Lorazepam) Stay in Your System?

Ativan is a medication belonging to the benzodiazepine class, also known as its generic form, lorazepam. It is best known for its anxiolytic (anti-anxiety) and sedative purposes. Ativan enhances the activity of gamma-aminobutyric acid (GABA), a neurotransmitter in the brain that has a calming effect.

Knowing how long lorazepam stays in your body is vital for several reasons. Drug testing for employment or legal purposes is standard, so understanding the Ativan detection window is essential. Even if you are taking benzos as prescribed, drug test evaluators need to know if Ativan may be detected in your body at therapeutic levels.

Additionally, understanding how long Ativan is in your system ensures effective treatment while minimizing side effects and avoiding unintentional misuse overdose. With this knowledge, you can make informed decisions about your daily activities and responsibilities.

Uses of Ativan

Ativan is a benzo prescribed for various reasons, particularly for the treatment of anxiety disorders. People may utilize Ativan or other benzos to manage sleep issues due to their sedative properties. Ativan is also widely used for seizure disorder management and as a sedation aid for surgical procedures.

Ativan is typically taken in tablet form but can be administered via oral solutions or injected. A healthcare professional determines the dosage and duration of treatment based on the patient’s condition and response to the medication.

Ideally, a substance like Ativan will only be used short-term to treat anxiety disorders while someone is learning behavioral strategies to cope with anxiety triggers (with psychotherapy or other mental health interventions). Misuse often begins when people use benzos for mild bouts of nervousness or stress that a round of helpful breathing techniques or other similar coping strategies can ease.

How Long Does Ativan Stay in Your System?

The length of time Ativan stays in your system varies based on several factors, including the method of administration, dosage, frequency of use, and metabolism. The type of test used to detect it can impact how long lorazepam can be found in your body. These timelines are approximate:

  • Blood – detectable in the blood for about 6-24 hours after last use
  • Urine – detectable in urine for up to 6 days after the previous dose
  • Saliva – detectable in saliva typically within 8 hours up to 2 days after last use
  • Hair – detectable in hair for up to a month or even longer following the previous use

What is the Ativan Half-Life?

A drug’s half-life describes the time it takes for the substance’s concentration to decrease by half, as tested in the blood. Ativan’s half-life ranges from 9 to 19 hours, meaning that it takes about 9 to 19 hours for the drug’s concentration in the bloodstream to decrease by half.
Understanding the half-life is essential for determining the dosing schedule and for managing potential withdrawal symptoms if discontinuing the use of lorazepam.
The half-time time frame can differ based on a few variables:

  • Age – Older adults may have a longer half-life due to a slower metabolism
  • Liver function – Impaired liver function can increase the half-life of lorazepam
  • Dosage and frequency – Higher or more frequent use can affect the drug’s elimination rate
  • Individual metabolic rate – A higher rate of metabolism will often process the drug more quickly through your system

Factors That Influence the Length of Time Ativan Stays in Your System

  • Dosage and frequency – Higher doses and frequent use can extend detection times
  • Metabolism – Individuals with faster metabolisms may eliminate Ativan more quickly.
  • Age – Older adults tend to have a slower metabolism, potentially extending the detection window
  • Body composition – Higher body fat may lead to longer retention as Ativan is fat-soluble.
  • Overall health – General health conditions can affect how quickly the body processes lorazepam
  • Drug interactions – Other medications and co-occurring substance use can influence how quickly Ativan is metabolized and excreted

False Positives

A false positive test, or a drug test that incorrectly shows up as positive for a particular substance, can occur with testing for benzos. False positives can occur due to cross-reactivity with other substances, whether they be prescription or recreational drugs.

Other benzodiazepines, such as Valium or Xanax, can be mistaken for Ativan in testing as well. Some SSRIs, like Zoloft, may also cause false positives.

It may be surprising to know that over-the-counter medications, such as ibuprofen and acid reflux drugs, have been reported to cause false positives for benzos anecdotally.

Ativan Addiction Treatment

Medications like Ativan are beneficial for their medically intended purposes but carry a risk of addiction. Misusing lorazepam once or twice can spiral into realizing you’ve developed a dependence. It’s alarming to recognize that your attachment to a medication could be an actual addiction issue.

Detoxification is often the first step in a comprehensive treatment plan for Ativan dependence or addiction. Following detoxification, individuals may engage in further treatment, such as individual and group therapy or a rehab program, to address underlying issues and prevent relapse.

doctor speaking with patient about how long adderall stays in the system

If you feel like you or a loved one is struggling with Ativan addiction, contact Vogue Recovery Centers today. You can access the help you deserve with locations in Las Vegas and Phoenix. Seeking help with addiction is a brave act, but it’s possible to navigate the process of treating Ativan addiction with support from professionals who care.

Kelsey Jones vrc az

Medically Reviewed by Kelsey Jones, MS, LPC

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